Oral Antiviral Drug Valacyclovir Hydrochloride for Infections Treatment 124832-27-5

Quick Details 

Product Name: Valacyclovir hydrochloride

CAS RN:124832-27-5

MF: C13H21ClN6O4

MW: 360.8

Chemicals;Nucleotides;Pharmaceuticals;API's;Valacyclovir;API

Melting point : 170-172°C 

Storage temp. : Refrigerator

Chemical Properties White Crystalline Powder

Package:25kg/barrel or as your inquiry 

Usage Acyclovir (A192400) impurity. The L-Valine ester prodrug of Acyclovir.

Usage Valaciclovir hydrochloride is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B.

Reference FOB Price:$0.3/g

MOQ:100g

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

 Skype/E-mail : summer at chembj.com

Valacyclovir Hydrochloride Description

Valacyclovir Hydrochloride is considered as an oral antiviral drug that is active in herpes viruses. This drug is primarily used to cure infections like cold sores, genital herpes, shingles and others. This also belongs to class of drugs known as the nucleoside analogs that primarily mimics the DNA's building blocks. It helps to prevent the herpes virus to multiply and spread in the body .

What is valacyclovir hydrochloride ?

Valacyclovir hydrochloride is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the following treatment and prevention uses for certain types of herpes simplex virus (HSV) :

To treat initial or recurrent episodes of genital herpes in healthy adults

To prevent genital herpes outbreaks in adults infected with HIV

To reduce the risk of transmitting genital herpes to other people

To treat cold sores (also known as herpes labialis or orolabial herpes) in adults and children

Valacyclovir hydrochloride is also approved for the following treatment uses for varicella zoster virus (VZV) infections :

To treat shingles (also known as herpes zoster) in adults

To treat chicken pox (also known as primary varicella infection) in children

HSV and VZV infections are opportunistic infections. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems-such as those infected with HIV-than in people with healthy immune systems. To learn more about opportunistic infections, read the AIDSinfo What is an Opportunistic Infection? fact sheet.Valacyclovir hydrochloride can also be used "off-label" to prevent and treat other opportunistic infections of HIV infection. "Off-label" use refers to use of an FDA-approved medicine in a manner different from that described on the medicine label. Good medical practice and the best interests of a patient sometimes require that a medicine be used "off-label."

What HIV-related opportunistic infections is valacyclovir hydrochloride used for ? 

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), includes recommendations on the HIV-related uses of valacyclovir hydrochloride to :

Prevent :

Orolabial lesions (cold sores) and genital lesions caused by HSV infection from recurring (called secondary prophylaxis or maintenance therapy). (The orolabial lesion use is an "off-label" use.)

Chicken pox (a VZV infection also known as primary varicella infection) from occurring in certain people who come in contact with someone who has active shingles or chicken pox. (This is called post-exposure prophylaxis.)

Treat :

HSV infections, including orolabial lesions (cold sores) and genital lesions.

VZV infections, including shingles, chicken pox, and acute retinal necrosis, which is an infection and necrotizing inflammation (causing tissue death) of the eye's retina.  

The above list may not include all of the HIV-related uses of valacyclovir hydrochloride recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.