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Antineoplastic High Purity Vinblastine Sulfate CAS 865-21-4
Antineoplastic High Purity Vinblastine Sulfate CAS 865-21-4
  • >= 10  Gram US $50.000
Supply Ability:
5000000 Gram/Grams per Month
Port:
Guangzhou
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Quantity:
Gram
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Place of Origin:
China (Mainland)
Brand Name:
Kafen
Model Number:
865-21-4
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Product Description

Antineoplastic High Purity Vinblastine Sulfate CAS 865-21-4



Basic info.


Vinblastine Sulfate

CAS No.: 865-21-4

Molecular Formula: C46H58N4O9. H2SO4

Molecular Weight: 909.06

Appearance: White to off-white crystalline powder

Assay: 95%-105%

Loss of drying: <12%

Action: Antitumor


Descriptions:


Mainly used for the treatment of solid tumor. For malignant lymphoma, testicular neoplasm and choriocarcinoma curative effect is better. For lung, breast, ovarian, skin cancer, renal mother cell tumor and monocytes leukaemia also have certain curative effect.

Pharmacology: Vinblastine Vinca plants for the oleander extract has anti-cancer activity of an alkaloid. Major inhibition of tubulin polymerization, preventing the formation of spindle microtubules, so stop in MID-mitosis. Role in the cell membrane can also interfere with membrane transport of amino acids, protein synthesis was inhibited, also inhibited RNA synthesis.


Applications:


A- Mainly used in the treatment of Hodgkin's disease, lymphatic reticulum cell sarcoma, chorionic carcinoma, testicular tumor. Is also effective for other malignant lymphoma.

B- For acute leukemia, mononuclear cell leukemia, lung cancer, breast cancer, ovarian cancer, kidney tumor, oral cancer, malignant melanoma, skin cancer have certain curative effect.

C- Treatment of idiopathic thrombocytopenic purpura.

D- Treatment of rheumatoid arthritis.


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