Pharmaceutical Polysorbate 80 Liquid Steroid Injection Conversion Solvent Tween 80

1.Basic Details

Product Name:Tween 80

CAS NO.:9005-65-6

Alias Polysorbate:80

EINECS: 500-019-9

Molecular formula:C26H34O4 

Molecular weight:1310

Purity: 99%

Grade:pharmaceutical grade,food grade

Appearance:Amber colored viscous liquid

Density:1.06-1.09 g/mL

Boiling point:> 100°C

Solubility in water:Very soluble

Viscosity:300-500 centistokes (25°C)

Application:Food,Health and Beauty,Medical

2.Description

Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. This synthetic compound is a viscous, water-soluble yellow liquid. 

3.Application

Food use:Polysorbate 80 is used as an emulsifier in foods.

For example in ice cream, polysorbate is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting. Adding this substance prevents milk proteins from completely coating the fat droplets. This allows them to join together in chains and nets, which hold air in the mixture, and provide a firmer texture that holds its shape as the ice cream melts.

Health and beauty use:Polysorbate 80 is also used as a surfactant in soaps and cosmetics, or a solubilizer such as in a mouthwash. The cosmetic grade of polysorbate 80 may have more impurities than the food grade.

Medical use:Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the manufacture of the popular antiarrhythmic amiodarone. It is also used as an excipient in some European and Canadian influenza vaccines.Influenza vaccines contain 25 μg of polysorbate 80 per dose. It is also used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth. It is also used as an emulsifier in the estrogen-regulating drug Estrasorb.