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4-Androstenedione (4-AD) Androtex CAS 63-05-8
4-Androstenedione (4-AD) Androtex CAS 63-05-8
  • >= 10  Kilogram US $50.000
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5000 Kilogram/Kilograms per Month
Port:
Guangzhou
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Quantity:
Kilogram
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Quick Details
Place of Origin:
China (Mainland)
Brand Name:
Kafen
Model Number:
63-05-8
Product Description

4-Androstenedione (4-AD) Androtex CAS 63-05-8



Quick Details:


4-Androstenedione 

Synonyms: Androtex; 4-Androstenedione(4AD);3,17-Dioxoandrost-4-Ene

CAS: 63-05-8 

MF: C19H26O2 

MW: 286.41

EINECS: 200-554-5 

Purity: 98.88% 

Characters: Near white crystalline powder, soluble in ethanol, insoluble in water 

Mini Order:  10g 


Description: 


Used for simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroid, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.


Applications:

 

4-Androstenedione is the common precursor of male and female sex hormones. Some 4-Androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.

 

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.


The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal ovary.


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China (Mainland) | Manufacturer

Experience:Established 2016

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