High Quality Female Steroids Estriol 50-27-1 Raw Hormone Powder

1.Quick Details:

Product Name: Estriol

Estriol Synonyms: TRIDESTRIN;(16-alpha,17-beta)-estra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol;(16-alpha,17-beta)-oestra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol;1,3,5-estratriene-3-beta,16-alpha,17-beta-triol;1,3,5-Estratriene-3beta,16-alpha,17-beta-triol;1,3,5-oestratriene-3-beta,16-alpha,17-beta-triol

CAS: 50-27-1

MF: C18H24O3

MW: 288.38

Estriol EINECS: 200-022-2

Product Categories: Steroids;Hormone;Biochemistry;Hydroxysteroids;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroid and Hormone;API;THEELOL;Hormone Drugs;Inhibitors

Mol File: 50-27-1.mol

Reference FOB Price:$1/g

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Production Capacity:5000kg/month

Shipping: DHL, EMS, FedEx, UPS

More details pls contact:Whatapp:86 13048470428  

Skype/E-mail : summer at chembj.com

2.Product Description:

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17-estradiol.

3.Product Application:

A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.

4.COA:

Test Items Specification Test Results

Description White or almost white crystalline powder White crystalline powder

Melting Point 191.0~193.0ºC 192ºC

Loss of drying ≤1.0% 0.5%

Heavy Metal ≤20ppm 15ppm

TLC Only one spot Only one spot

Assay ≥99.5% 99.91%

Conclusion It complies with the USP 32