Anti-Depress Drugs Trazodone Hydrochloride CAS: 25332-39-2 for Anxiety Disorder

Basic Info.

Product Name: Trazodone hydrochloride

Synonyms: TRAZODONE HCL;TRAZODONE HYDROCHLORIDE;)-onehcl;2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2h;af1161;kb-831;molipaxin;pragmazone

CAS: 25332-39-2

MF: C19H23Cl2N5O

MW: 408.32

EINECS: 246-855-5

Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;ANAHIST

Mol File: 25332-39-2.mol

Trazodone hydrochloride Chemical Properties

Melting point: 223-226°C

storage temp.: -20°C Freezer

solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL

form: powder

Purity:99%

color: off-white

Package:1kg/foil bag or as your inquiry

Shelf life:2 years

Standard:Enterprise Standard 

Price:negotiable 

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk

Payment: Western Union, Moneygram, T/T, Bitcoin

Delivery time: Parcel can be sent out within 24 hours after your payment, 4~7 days to arrive.

More details pls contact:Whatapp:86 13048470428  

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What is trazodone?

Trazodone is an antidepressant medicine. It affects chemicals in the brain that may be unbalanced in people with depression. It is a phenylpiperazine compound. 

Trazodone is used to treat major depressive disorder.

Usage & Effect:

The primary use of trazodone is the treatment of major depression. Data from open and double-blind trials suggest the antidepressant efficacy of trazodone is comparable to that of amitriptyline, doxepin, and mianserin. Also, trazodone showed anxiolytic properties, low cardiotoxicity, and relatively mild side effects. Because trazodone has minimal anticholinergic activity, it was especially welcomed as a treatment for geriatric patients with depression when it first became available. Three double-blind studies reported trazodone has antidepressant efficacy similar to that of other antidepressants in geriatric patients. However, a side effect of trazodone, orthostatic hypotension, which may cause dizziness and increase the risk of falling, can have devastating consequences for elderly patients; thus, this side effect, along with sedation, often makes trazodone less acceptable for this population, compared with newer compounds that share its lack of anticholinergic activity but not the rest of its side-effect profile. Still, trazodone is often helpful for geriatric patients with depression who have severe agitation and insomnia.[6] Trazodone has also been reported to have antianxiety properties. In a randomized, double-blind, placebo-controlled trial, the anxiolytic efficacy of trazodone was comparable to that of diazepam in weeks 3-8 of treatment for generalized anxiety disorder, although patients treated with diazepam had greater improvement during the first 2 weeks of treatment. Early case reports had indicated that trazodone is associated with improvement in obsessive-compulsive disorder, but a double-blind, placebo-controlled study found that trazodone lacked antiobsessional effects. Many clinicians use low-dose trazodone as an alternative to benzodiazepines for the treatment of insomnia.

Trazodone Hydrochloride Usage :

Major Depressive Disorder

Schizophrenic Disorder

Alcohol Dependence

Anxiety disorder