Clobetasol Propionate
English Synonyms: 17-propionate;cgp9555;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;CLOBESTASOL PROPIONATE;CLOBETASOL-17-PROPIONATE;CLOBETASOLE PROPIONATE;CLOBETASOL PROPIONATE
Clobetasol Propionate CAS NO.: 25122-46-7
Clobetasol Propionate Assay: 98%
Clobetasol Propionate Molecular Formula:C25H32ClFO5
Clobetasol Propionate Molecular Weight:466.97
Clobetasol Propionate Quality Standard: USP31
Clobetasol Propionate Packing:foil bag/tin
Clobetasol Propionate Usage: Adrenal cortical hormone and adrenocorticotropic hormone class medicine
Product description:
Pharmacology toxicology:
This product is rapid, the current clinical application of effective topical corticosteroide medicine effect of a strong. Has the strong capillary contraction, the anti-inflammatory effects of hydrocortisone for 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. Systemic adverse reactions for 3 times fluocinolone, anhydrous sodium retention effect, have certain promote sodium, potassium excretion.
COA
Item | Specification | Result |
Appearance | White to cream, crystalline powder | White crystalline powder |
Identification (by IR) | Conforms to the CRS spectrum | Conforms |
Melting Point | Approximately 196 °C | 196°C |
Specific rotation | +98°~+104°(dried substance) | +99.7° |
Loss on drying | ≤2.0% | 0.2% |
Residue on ignition | ≤0.1% | 0.06% |
Heavy metals | ≤20ppm | Conforms |
Related substance (by HPLC) | Any impurity ≤1.0% | 0.22% |
Total impurities ≤2.0% | 0.31% | |
Assay(by HPLC) | Contains 97.0% to 102% of C25H32CIFO5 calculated on dried basis | 99.9% |
Residual solvents | Ethanol ≤3000ppm | 262ppm |
Aceton ≤500ppm | Undetected (LOD 4ppm) | |
Pyriding ≤100ppm | Undetected (LOD 3ppm) | |
N,N-Dimethylformamide ≤100ppm | Undetected (LOD 10ppm) | |
Conclusion | Meet the specification according to USP35 |
Usage:
A. Clobetasol propionate is a synthetic high topical corticosteroide. Has a strong anti-inflammatory, anti itching and capillary contraction, the anti-inflammatory effects of hydrocortisone is about 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. At the same time has an inhibitory role in cell mitosis, can effectively penetrate into the skin stratum corneum.
B. External apply to chronic eczema, psoriasis, neurodermatitis, palmoplantar pustulosis, lichen planus, discoid lupus erythematosus, glucocorticoid, topical treatment of pruritic effective and non inflammatory skin disease.
C. Has the inhibitory effect of anti-inflammatory, anti allergic, anti proliferation, immune.
Products: Compound ketoconazole can. Miconazole nitrate, vitamin A acid cream and liniment.
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Flurogestone acetate | CAS: 2529-45-5 |
Cortisone Acetate | CAS: 50-04-4 |
About us
Place of Origin: Guangzhou
Brand Name:Quanao
Certification:USP and SGS
Minimum order quantity:10g
Delivery Time: 4-6 days
Deliver From: Hongkong and Guangdong China
Delivery Means: DHL or UPS or FEDEX or Private Courier Service or EMS
Payment: Western Union, Bank transfer, Money gram and Bitcoin
Packing: Very discreetly, with rich experience shipping to USA, Canada, UK and no doubt 100% safe delivery guaranteed.