Product Details

Estogen Hormone Raw Powder  CAS: 630-56-8  17a-Hydroxyprogesterone 

Basic Views

Product Name: 17a-Hydroxyprogesterone 

Synonyms: PREGN-4-ENE-3,20-DIONE HEXANOATE;17-((1-oxohexyl)oxy)-pregn-4-ene-20-dione;17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione;17a-hydroxyprogesteronehexanoate;17-alpha-Hexanoyloxypregn-4-ene-3,20-dione;17alpha-Hydroxyprogesterone n-caproate;17-alpha-hydroxyprogesteronen-caproate;17-Hydroxypregn-4-ene-3,20-dione caproate 

CAS: 630-56-8 

MF: C27H40O4 

MW: 428.6 

EINECS: 211-138-8




HS Code: 29163920




Shelf life:2 years




Reference FOB Price:$1/g

MOQ:10g




Production Capacity:5000kg/month




Shipping: DHL, EMS, FedEx, UPS

More details pls contact:Whatapp:86 13048470428  

Skype/E-mail : summer at chembj.com




Delivery time: Parcel can be sent out within 24 hours after your payment, 4~7 days to arrive.




17a-Hydroxyprogesterone Description:

(1). 17α-Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid).

(2). 17α-Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.

(3). The US FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy.




17a-Hydroxyprogesterone Specifications:




Standard:USP31

   

Items Standard Resutls

Description White or almost white crystalline powder, odorless Conforms

Solubility insoluble in water, solube in ether, slightly soluble in benzene Conforms

Specific Optical Rotation +58°---+64° (1% chloroform Solution) 60.3°

Melting Point about 120  -124 ºC 123ºC

Water ≤0.1% 0.05%

Free N-Caproic Acid ≤0.58% 0.20%

Ordinary Impurities ≤2.0% conforms

Residual Solvents Methanol ≤ 3000PPM 1280PPM

Ethanol≤5000PPM 1500PPM

Dichloromethane ≤ 600PPM 80PPM

Assay 97.0%--103.0% 99.30%

 




 Application:




   This medication is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin). It is not known how it works to prevent preterm labor.

   This medication is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). It is also not intended to stop active preterm labor.

Side effects:

   Pain, swelling, itching, bruising, or a lump at the injection site may occur. Nausea ordiarrhea may also occur.